Hope this message finds you well and healthy. I know a pretty good time has passed since the last post here but this might be still interesting for others just at the begining with their journeys. Although several drugs and protocols are available to stimulate the ovaries to produce extra eggs for IVF, most clinics utilize only a few of these stimulation protocols. One of the more common IVF protocols is called luteal suppression. It involves suppression of the ovaries using a Lupron during the luteal phase of the menstrual cycle preceding the planned IVF treatment cycle. Once the ovaries are suppressed, ovarian stimulation is accomplished with daily injections of Gonal-F, Follistim. Lupron is usually continued until the day of the HCG trigger shot. Another common protocol is called flare stimulation. In this case the woman does not take any medications until the second day of her menstrual cycle. At that time a microdose of Lupron is used to flare the pituitary gland and induce it to release its store of FSH and LH. A third, more recent option is GnRH-antagonist stimulation, in which GnRH antagonists are added later in the stimulation to prevent premature ovulation.Once the follicles have reached a specific size – usually 12 to 14 mm, the woman begins the GnRH-antagonist medication. Some reproductive endocrinologists prescribe oral contraceptive pills to their female patients prior to beginning the actual ovarian stimulation drugs, but this practice varies between patients and fertility clinics. he type of protocol selected for any patient (i.e., luteal suppression, flare stimulation or GnRH antagonist) depends on the individual patient and the philosophy of the fertility clinic. Factors that may influence the type of stimulation protocol selected include the patient’s age, her day 3 hormone levels, her follicle antral count as determined by ultrasound, and her previous responses to any other attempts at ovarian stimulation. As you can see meds do play an important role in the whole infertility treatment process.